Women who want the strongest available option for appetite and metabolic reset — especially if a GLP-1-only medication hasn't fully worked for you.
The Reset Protocol+
Tirzepatide — dual-action GLP-1/GIP support paired with the labs and lifestyle protocol that keep it working, and keep muscle on.
- —Reduces appetite and food noise, targeting two hormone pathways at once
- —Often associated with greater average results than GLP-1-only medications
- —Dosed conservatively — we start low and adjust with you, not for you
Because we treat metabolic health as a whole-body, multi-system process — not just the number on the scale — most patients reach their goals at our lowest effective dose. If your provider determines you need more over time, pricing adjusts transparently with your dose.
Reviewed and prescribed, if you qualify, by our nationwide network of MDs & DOs.
Tirzepatide: dual GLP-1 + GIP receptor agonist, once weekly
Tirzepatide works like semaglutide's GLP-1 mechanism, but adds a second pathway: GIP, another natural gut peptide hormone involved in appetite and blood sugar regulation. Targeting both at once is why tirzepatide is often associated with stronger average results in clinical trials than GLP-1-only medications. It's still not a shortcut — it's a tool that quiets appetite and food noise enough for the rest of your plan to actually work.
Individual results and eligibility vary. Your intake and labs determine what's right for you.
Side effects, honestly.
Tirzepatide is generally well-tolerated, and most side effects are mild, dose-related, and ease as your body adjusts. Your provider reviews your health history before prescribing, starts you at the lowest effective dose, and checks in with you as you go. This is not a complete list. Full prescribing and safety information is available on request, or message your care team with questions.
- Nausea, especially in the first weeks
- Diarrhea or constipation
- Decreased appetite
- Fatigue
- Injection site reactions
- Headache
- Gallstones or gallbladder discomfort
- Dizziness
- Heartburn or reflux
- Signs of pancreatitis: severe abdominal pain, often with nausea or vomiting
- Signs of a severe allergic reaction: swelling, hives, trouble breathing
- Signs of gallbladder disease requiring treatment
- Signs of kidney problems, often related to dehydration from GI symptoms
- Vision changes
GLP-1/GIP medications carry a boxed warning regarding thyroid C-cell tumors observed in animal studies; this is not for you if you or your family have a history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. This product is not for use by anyone under 18, anyone with a personal or family history of certain thyroid cancers, a history of pancreatitis, or anyone who is pregnant or trying to become pregnant.
The Reset Protocol+ vs. The Reset Protocol
Your provider will confirm which is right for you based on labs, history, and goals — you can always switch.
It's easy to get started
Complete your evaluation
Tell us your health history and goals. If you don't have recent labs, we'll help you get them.
Get your prescription
A physician in our nationwide MD/DO network reviews your intake and labs and starts you at the lowest effective dose. Message your care team anytime.
Adjust as you go
Your Reset Protocol+ ships to your door. Most women notice appetite changes within the first couple of weeks, with regular check-ins to fine-tune your dose only if you need it.
Common questions
It delivers tirzepatide, a dual GLP-1/GIP receptor agonist, in a once-weekly injection — targeting two of your body's own metabolic hormone pathways to reduce appetite and improve blood sugar regulation.
Mounjaro and Zepbound are brand-name, FDA-approved tirzepatide products. The Reset Protocol+ uses compounded tirzepatide, prepared by a licensed 503A pharmacy — it's not FDA-approved as a compounded product, but it allows for personalized dosing and is typically more accessible in cost. Your provider can help you understand what's right for you.
Many women start with the Reset Protocol+ specifically because of its dual-hormone mechanism, but your provider will help you decide based on your labs, history, and goals — including whether you've tried a GLP-1-only medication before.
Many women notice reduced appetite within the first couple of weeks; full effect builds over the first 1–2 months as your dose is optimized.
One subcutaneous injection, once weekly, at home — your provider and care team walk you through technique and timing.
Your dose is set by your provider and adjusted over time. Pricing follows it — here's the full ladder, so there's nothing to discover later.
Yes. Baseline labs help your provider confirm eligibility and starting dose.
Every Reset Protocol+ order is reviewed and, if appropriate, prescribed by a licensed MD or DO in The Wellness Abode's nationwide physician network — not by Dr. Esguerra directly, whose role is your functional medicine evaluation and ongoing care plan.
This product is compounded and is not approved or evaluated for safety, efficacy, or quality by the FDA.
Individual results vary. This is not a complete list of risks or side effects — full prescribing information is available on request.